Interneurons secrete prosaposin, a neurotrophic factor, to attenuate kainic acid-induced neurotoxicity
Prosaposin (PS) is a secretory neurotrophic factor, as well as a regulator of lysosomal enzymes.We previously reported the up-regulation of PS and the possibility of its axonal transport by GABAergic interneurons after exocitotoxicity induced by kainic acid (KA), a glutamate analog.In the present study, we performed double immunostaining with PS an